Hypersensitivity to the active substances or, to any of the excipients, or to other sulphonamide-derived substances (hydrochlorothiazide is a sulphonamide-derived substance).
Pregnancy.
Lactation.
Choleastasis and biliary obstructive disorders.
Severe hepatic impairment, coma hepatricum, hepatic precoma.
Severe renal impairment (creatinine clearance < 30 ml/min) or serum creatinine > 1.8 mg/100 ml), anuria, or acute glomerulonephritis.
Refractory hypokalaemia, hypercalcaemia.
Therapy-refractory hyponatraemia.
Hypovolaemia.
Symptomatic hyperuricaemia/gout.
The concomitant use of MICARDIS PLUS with aliskiren is contraindicated in patients with diabetes mellitus or renal impairment (GFR < 60 ml/min/1.73 m2).
In case of rare hereditary conditions that may be incompatible with an excipient of the product (see Precautions), the use of the product is contraindicated.